Potassium azeloyl diglycinate
INCI Potassium Azeloyl Diglycinate
A water-soluble derivative of azelaic acid. Chosen for a more even-looking tone, a matter finish on oily zones and a gentler feel than azelaic acid itself.
- Also known as
- Azeloglicina, Azeloyl diglycinate, PAD
Potassium azeloyl diglycinate is a derivative of azelaic acid in which the acid is bound to two glycine molecules and neutralised as a potassium salt. The change matters for formulation: azelaic acid is poorly soluble in water and gritty at useful levels, while this derivative dissolves cleanly into a light, clear serum at a skin-compatible pH.
Supplier and cosmetic literature describe it as sebum-normalising and tone-evening, with a moisturising contribution from the glycine portion. In use it is chosen for formulas aimed at the look of post-blemish marks, patchy tone and shine on oily zones, particularly where a gentler feel than azelaic acid is wanted.
It is non-acidic, does not increase sun sensitivity and sits comfortably alongside niacinamide, tranexamic acid and hydroxy acids in a multi-active formula. Most of the published evidence sits with the parent molecule, azelaic acid, so we label this ingredient literature-backed at the level of mechanism and supplier data rather than borrowing the parent molecule's claims.
Where you will find it.
- Multi-Active Complex Face Serum Serum In the INCI
Percentages are read from each product's stated active complex. Where none is stated the ingredient appears in the full INCI only.
Is this the same as azelaic acid?
It is a derivative, not the acid itself. It shares the azelaic backbone but is water-soluble and neutral, which is why it works in a clear serum without the grit or sting some people notice with azelaic acid creams.
Can I use it every day?
Yes. It is non-exfoliating and well tolerated. As with any new active, patch-test first.
Why is the evidence tier "literature-backed" rather than clinical?
The strongest published data is on azelaic acid. The derivative is supported by supplier studies and mechanism work. We say so plainly rather than borrow the parent molecule's claims.
- CosIng, Potassium Azeloyl Diglycinate (EU cosmetic ingredient database) ec.europa.eu/growth/tools-databases/cosing/
- Sieber MA, Hegel JK. Azelaic acid: properties and mode of action. Skin Pharmacol Physiol. 2014;27(Suppl 1):9–17.
- Sinerga S.p.A. Azeloglicina technical dossier (supplier data).